Optogenetic control of nuclear protein export

Light-inducible control of protein subcellular localization holds great promise for synthetic biology applications and insights into basic cell biology. Here the authors develop a genetically-encoded light-inducible nuclear export system and apply it to a synthetic repressor and p53 transcriptional...

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Autores principales:	Dominik Niopek, Pierre Wehler, Julia Roensch, Roland Eils, Barbara Di Ventura
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8e5dd11fb4324000ad98350457e5bc70
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spelling	oai:doaj.org-article:8e5dd11fb4324000ad98350457e5bc702021-12-02T14:39:14ZOptogenetic control of nuclear protein export10.1038/ncomms106242041-1723https://doaj.org/article/8e5dd11fb4324000ad98350457e5bc702016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10624https://doaj.org/toc/2041-1723Light-inducible control of protein subcellular localization holds great promise for synthetic biology applications and insights into basic cell biology. Here the authors develop a genetically-encoded light-inducible nuclear export system and apply it to a synthetic repressor and p53 transcriptional activity.Dominik NiopekPierre WehlerJulia RoenschRoland EilsBarbara Di VenturaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Dominik Niopek Pierre Wehler Julia Roensch Roland Eils Barbara Di Ventura Optogenetic control of nuclear protein export
description	Light-inducible control of protein subcellular localization holds great promise for synthetic biology applications and insights into basic cell biology. Here the authors develop a genetically-encoded light-inducible nuclear export system and apply it to a synthetic repressor and p53 transcriptional activity.
format	article
author	Dominik Niopek Pierre Wehler Julia Roensch Roland Eils Barbara Di Ventura
author_facet	Dominik Niopek Pierre Wehler Julia Roensch Roland Eils Barbara Di Ventura
author_sort	Dominik Niopek
title	Optogenetic control of nuclear protein export
title_short	Optogenetic control of nuclear protein export
title_full	Optogenetic control of nuclear protein export
title_fullStr	Optogenetic control of nuclear protein export
title_full_unstemmed	Optogenetic control of nuclear protein export
title_sort	optogenetic control of nuclear protein export
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/8e5dd11fb4324000ad98350457e5bc70
work_keys_str_mv	AT dominikniopek optogeneticcontrolofnuclearproteinexport AT pierrewehler optogeneticcontrolofnuclearproteinexport AT juliaroensch optogeneticcontrolofnuclearproteinexport AT rolandeils optogeneticcontrolofnuclearproteinexport AT barbaradiventura optogeneticcontrolofnuclearproteinexport
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Optogenetic control of nuclear protein export

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