Modulation of calcium-dependent inactivation of L-type Ca2+ channels via β-adrenergic signaling in thalamocortical relay neurons.

Neuronal high-voltage-activated (HVA) Ca(2+) channels are rapidly inactivated by a mechanism that is termed Ca(2+)-dependent inactivation (CDI). In this study we have shown that β-adrenergic receptor (βAR) stimulation inhibits CDI in rat thalamocortical (TC) relay neurons. This effect can be blocked...

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Main Authors: Vladan Rankovic, Peter Landgraf, Tatyana Kanyshkova, Petra Ehling, Sven G Meuth, Michael R Kreutz, Thomas Budde, Thomas Munsch
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
Subjects:
R
Q
Online Access:https://doaj.org/article/8e69a9b83c114c408b0289f5ccd80db9
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