The essential elements for the noncovalent association of two DNA ends during NHEJ synapsis

During a process termed synapsis, the two DNA ends at a double-strand break (DSB) are brought together into physical proximity. Here, the authors use a single-molecule FRET approach with purified proteins to investigate the mechanism of synapsis in DSB repair by non-homologous DNA end joining (NHEJ)...

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Auteurs principaux: Bailin Zhao, Go Watanabe, Michael J. Morten, Dylan A. Reid, Eli Rothenberg, Michael R. Lieber
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/8ea44050cb614a2e9f26069961a8fcee
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