The essential elements for the noncovalent association of two DNA ends during NHEJ synapsis

The essential elements for the noncovalent association of two DNA ends during NHEJ synapsis

During a process termed synapsis, the two DNA ends at a double-strand break (DSB) are brought together into physical proximity. Here, the authors use a single-molecule FRET approach with purified proteins to investigate the mechanism of synapsis in DSB repair by non-homologous DNA end joining (NHEJ)...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Bailin Zhao, Go Watanabe, Michael J. Morten, Dylan A. Reid, Eli Rothenberg, Michael R. Lieber
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/8ea44050cb614a2e9f26069961a8fcee
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:8ea44050cb614a2e9f26069961a8fcee
record_format dspace
spelling oai:doaj.org-article:8ea44050cb614a2e9f26069961a8fcee2021-12-02T14:38:45ZThe essential elements for the noncovalent association of two DNA ends during NHEJ synapsis10.1038/s41467-019-11507-z2041-1723https://doaj.org/article/8ea44050cb614a2e9f26069961a8fcee2019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11507-zhttps://doaj.org/toc/2041-1723During a process termed synapsis, the two DNA ends at a double-strand break (DSB) are brought together into physical proximity. Here, the authors use a single-molecule FRET approach with purified proteins to investigate the mechanism of synapsis in DSB repair by non-homologous DNA end joining (NHEJ).Bailin ZhaoGo WatanabeMichael J. MortenDylan A. ReidEli RothenbergMichael R. LieberNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Bailin Zhao
Go Watanabe
Michael J. Morten
Dylan A. Reid
Eli Rothenberg
Michael R. Lieber
The essential elements for the noncovalent association of two DNA ends during NHEJ synapsis
description During a process termed synapsis, the two DNA ends at a double-strand break (DSB) are brought together into physical proximity. Here, the authors use a single-molecule FRET approach with purified proteins to investigate the mechanism of synapsis in DSB repair by non-homologous DNA end joining (NHEJ).
format article
author Bailin Zhao
Go Watanabe
Michael J. Morten
Dylan A. Reid
Eli Rothenberg
Michael R. Lieber
author_facet Bailin Zhao
Go Watanabe
Michael J. Morten
Dylan A. Reid
Eli Rothenberg
Michael R. Lieber
author_sort Bailin Zhao
title The essential elements for the noncovalent association of two DNA ends during NHEJ synapsis
title_short The essential elements for the noncovalent association of two DNA ends during NHEJ synapsis
title_full The essential elements for the noncovalent association of two DNA ends during NHEJ synapsis
title_fullStr The essential elements for the noncovalent association of two DNA ends during NHEJ synapsis
title_full_unstemmed The essential elements for the noncovalent association of two DNA ends during NHEJ synapsis
title_sort essential elements for the noncovalent association of two dna ends during nhej synapsis
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/8ea44050cb614a2e9f26069961a8fcee
work_keys_str_mv AT bailinzhao theessentialelementsforthenoncovalentassociationoftwodnaendsduringnhejsynapsis
AT gowatanabe theessentialelementsforthenoncovalentassociationoftwodnaendsduringnhejsynapsis
AT michaeljmorten theessentialelementsforthenoncovalentassociationoftwodnaendsduringnhejsynapsis
AT dylanareid theessentialelementsforthenoncovalentassociationoftwodnaendsduringnhejsynapsis
AT elirothenberg theessentialelementsforthenoncovalentassociationoftwodnaendsduringnhejsynapsis
AT michaelrlieber theessentialelementsforthenoncovalentassociationoftwodnaendsduringnhejsynapsis
AT bailinzhao essentialelementsforthenoncovalentassociationoftwodnaendsduringnhejsynapsis
AT gowatanabe essentialelementsforthenoncovalentassociationoftwodnaendsduringnhejsynapsis
AT michaeljmorten essentialelementsforthenoncovalentassociationoftwodnaendsduringnhejsynapsis
AT dylanareid essentialelementsforthenoncovalentassociationoftwodnaendsduringnhejsynapsis
AT elirothenberg essentialelementsforthenoncovalentassociationoftwodnaendsduringnhejsynapsis
AT michaelrlieber essentialelementsforthenoncovalentassociationoftwodnaendsduringnhejsynapsis
_version_ 1718390907404812288

Ejemplares similares