Whole genome sequencing of nearly isogenic WMI and WLI inbred rats identifies genes potentially involved in depression and stress reactivity

Abstract The WMI and WLI inbred rats were generated from the stress-prone, and not yet fully inbred, Wistar Kyoto (WKY) strain. These were selected using bi-directional selection for immobility in the forced swim test and were then sib-mated for over 38 generations. Despite the low level of genetic...

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Autores principales: Tristan V. de Jong, Panjun Kim, Victor Guryev, Megan K. Mulligan, Robert W. Williams, Eva E. Redei, Hao Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/8eb44956bc7749e0b76370da72aeaff9
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