Comparison of the TLR4/NFκB and NLRP3 signalling pathways in major organs of the mouse after intravenous injection of lipopolysaccharide

Context: Lipopolysaccharide (LPS) is often used to induce immunoinflammatory reactions. TLR4/NFκB and NLRP3 signalling are major factors for inflammation. Dexamethasone (DXM) has an anti-immunoinflammatory effect. Objective: To investigate the inflammatory reaction in pathological changes of organs...

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Bibliographic Details
Main Authors: Qin Gong, Luling He, Mulan Wang, Shasha Zuo, Hongwei Gao, Yulin Feng, Lijun Du, Yingying Luo, Jun Li
Format: article
Language:EN
Published: Taylor & Francis Group 2019
Subjects:
lps
Online Access:https://doaj.org/article/8eb60239c687418bac2d7ea1d089d64b
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