Increased Survival in B-Cell-Deficient Mice during Experimental Cerebral Malaria Suggests a Role for Circulating Immune Complexes

ABSTRACT The pathogenesis of malaria, an insect-borne disease that takes millions of lives every year, is still not fully understood. Complement receptor 1 (CR1) has been described as a receptor for Plasmodium falciparum, which causes cerebral malaria in humans. We investigated the role of CR1 in an...

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Bibliographic Details
Main Authors: Rosane B. de Oliveira, Jennifer P. Wang, Sanjay Ram, Ricardo T. Gazzinelli, Robert W. Finberg, Douglas T. Golenbock
Format: article
Language:EN
Published: American Society for Microbiology 2014
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Online Access:https://doaj.org/article/8ee36fc27a6d4abea7f1b4c1d53bd13d
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