Antihypertensive drug guanabenz is active in vivo against both yeast and mammalian prions.
<h4>Background</h4>Prion-based diseases are incurable transmissible neurodegenerative disorders affecting animals and humans.<h4>Methodology/principal findings</h4>Here we report the discovery of the in vivo antiprion activity of Guanabenz (GA), an agonist of alpha2-adrenergi...
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| Autores principales: | , , , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Public Library of Science (PLoS)
2008
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/8eefe3241ca1455293c7d0b0209d1fe1 |
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