Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells

Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells

A vaccine to generate durable HIV broadly neutralizing antibodies (bnAb) from engineered B cells holds promise as an HIV functional cure. Here, the authors show that CRISPR/Cas-modified B cells expressing bnAbs as functional antigen receptors can be immunized to generate long-lived, germinal centre...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Deli Huang, Jenny Tuyet Tran, Alex Olson, Thomas Vollbrecht, Mary Tenuta, Mariia V. Guryleva, Roberta P. Fuller, Torben Schiffner, Justin R. Abadejos, Lauren Couvrette, Tanya R. Blane, Karen Saye, Wenjuan Li, Elise Landais, Alicia Gonzalez-Martin, William Schief, Ben Murrell, Dennis R. Burton, David Nemazee, James E. Voss
Format: article
Langue:EN
Publié: Nature Portfolio 2020
Sujets:
Science
Q
Accès en ligne:https://doaj.org/article/8f0e41a577a24e6390766e0efaf6153c
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Internet

https://doaj.org/article/8f0e41a577a24e6390766e0efaf6153c

Documents similaires