TRPV4 is activated by mechanical stimulation to induce prostaglandins release in trabecular meshwork, lowering intraocular pressure.

Trabecular meshwork constitutes the conventional outflow pathway and controls intraocular pressure by regulating aqueous outflow. Mechanical stimulation has been studied as one of the triggers to regulate aqueous outflow in trabecular meshwork, but it is not well understood. We investigated that how...

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Autores principales: Takatoshi Uchida, Shota Shimizu, Reiko Yamagishi, Suzumi M Tokuoka, Yoshihiro Kita, Rei Sakata, Megumi Honjo, Makoto Aihara
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/8f21891e3fc246dcaaef2b5d7a54f8db
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