Immunologically programming the tumor microenvironment induces the pattern recognition receptor NLRC4-dependent antitumor immunity

Background The efficacy of cancer immunotherapy can be limited by the poor immunogenicity of cancer and the immunosuppressive tumor microenvironment (TME). Immunologically programming the TME and creating an immune-inflamed tumor phenotype is critical for improving the immune-responsiveness of cance...

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Main Authors: Elizabeth Repasky, Harry D Bear, Fang Yuan, Xiaofei Yu, Wenjie Liu, Shixian Chen, Xueqian Cheng, Patrick A Paez, Tuanwei Sun, Chunyan Wei, Joseph W Landry, Andrew S Poklepovic, John R Subjeck, Chunqing Guo, Xiang-Yang Wang
Format: article
Language:EN
Published: BMJ Publishing Group 2021
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Online Access:https://doaj.org/article/8f4a5899c7754e49ab4f859993919521
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