The Membrane Protein of Severe Acute Respiratory Syndrome Coronavirus Functions as a Novel Cytosolic Pathogen-Associated Molecular Pattern To Promote Beta Interferon Induction via a Toll-Like-Receptor-Related TRAF3-Independent Mechanism
ABSTRACT Most of the intracellular pattern recognition receptors (PRRs) reside in either the endolysosome or the cytoplasm to sense pathogen-derived RNAs, DNAs, or synthetic analogs of double-stranded RNA (dsRNA), such as poly(I:C). However, it remains elusive whether or not a pathogen-derived prote...
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| Autores principales: | , |
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| Formato: | article |
| Lenguaje: | EN |
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American Society for Microbiology
2016
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/8f4b76d71301487ab62c82f108b62a79 |
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