<i>Bis</i>(Tryptophan) Amphiphiles Form Ion Conducting Pores and Enhance Antimicrobial Activity against Resistant Bacteria

The compounds referred to as <i>bis</i>(tryptophan)s (BTs) have shown activity as antimicrobials. The hypothesis that the activity of these novel amphiphiles results from insertion in bilayer membranes and transport of cations is supported by planar bilayer voltage-clamp studies reported...

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Autores principales: Mohit Patel, Saeedeh Negin, Joseph Meisel, Shanheng Yin, Michael Gokel, Hannah Gill, George Gokel
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/8f649761008d4153a5a2cd09c744493e
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