Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice

Titin determines the elasticity of the sarcomere and integrates into both the Z-disc and the M-band. Here, the authors generate a BioID mouse to study the titin interactome at the Z-disc region in neonatal and adult heart and skeletal muscle.

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Autores principales: Franziska Rudolph, Claudia Fink, Judith Hüttemeister, Marieluise Kirchner, Michael H. Radke, Jacobo Lopez Carballo, Eva Wagner, Tobias Kohl, Stephan E. Lehnart, Philipp Mertins, Michael Gotthardt
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/8f93ea653e124b8e83b6b456aadd7c7e
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