Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice

Titin determines the elasticity of the sarcomere and integrates into both the Z-disc and the M-band. Here, the authors generate a BioID mouse to study the titin interactome at the Z-disc region in neonatal and adult heart and skeletal muscle.

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Autores principales:	Franziska Rudolph, Claudia Fink, Judith Hüttemeister, Marieluise Kirchner, Michael H. Radke, Jacobo Lopez Carballo, Eva Wagner, Tobias Kohl, Stephan E. Lehnart, Philipp Mertins, Michael Gotthardt
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8f93ea653e124b8e83b6b456aadd7c7e
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spelling	oai:doaj.org-article:8f93ea653e124b8e83b6b456aadd7c7e2021-12-02T17:40:05ZDeconstructing sarcomeric structure–function relations in titin-BioID knock-in mice10.1038/s41467-020-16929-82041-1723https://doaj.org/article/8f93ea653e124b8e83b6b456aadd7c7e2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16929-8https://doaj.org/toc/2041-1723Titin determines the elasticity of the sarcomere and integrates into both the Z-disc and the M-band. Here, the authors generate a BioID mouse to study the titin interactome at the Z-disc region in neonatal and adult heart and skeletal muscle.Franziska RudolphClaudia FinkJudith HüttemeisterMarieluise KirchnerMichael H. RadkeJacobo Lopez CarballoEva WagnerTobias KohlStephan E. LehnartPhilipp MertinsMichael GotthardtNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Franziska Rudolph Claudia Fink Judith Hüttemeister Marieluise Kirchner Michael H. Radke Jacobo Lopez Carballo Eva Wagner Tobias Kohl Stephan E. Lehnart Philipp Mertins Michael Gotthardt Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice
description	Titin determines the elasticity of the sarcomere and integrates into both the Z-disc and the M-band. Here, the authors generate a BioID mouse to study the titin interactome at the Z-disc region in neonatal and adult heart and skeletal muscle.
format	article
author	Franziska Rudolph Claudia Fink Judith Hüttemeister Marieluise Kirchner Michael H. Radke Jacobo Lopez Carballo Eva Wagner Tobias Kohl Stephan E. Lehnart Philipp Mertins Michael Gotthardt
author_facet	Franziska Rudolph Claudia Fink Judith Hüttemeister Marieluise Kirchner Michael H. Radke Jacobo Lopez Carballo Eva Wagner Tobias Kohl Stephan E. Lehnart Philipp Mertins Michael Gotthardt
author_sort	Franziska Rudolph
title	Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice
title_short	Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice
title_full	Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice
title_fullStr	Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice
title_full_unstemmed	Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice
title_sort	deconstructing sarcomeric structure–function relations in titin-bioid knock-in mice
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/8f93ea653e124b8e83b6b456aadd7c7e
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Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice

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