Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice
Titin determines the elasticity of the sarcomere and integrates into both the Z-disc and the M-band. Here, the authors generate a BioID mouse to study the titin interactome at the Z-disc region in neonatal and adult heart and skeletal muscle.
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Main Authors: | Franziska Rudolph, Claudia Fink, Judith Hüttemeister, Marieluise Kirchner, Michael H. Radke, Jacobo Lopez Carballo, Eva Wagner, Tobias Kohl, Stephan E. Lehnart, Philipp Mertins, Michael Gotthardt |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
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Subjects: | |
Online Access: | https://doaj.org/article/8f93ea653e124b8e83b6b456aadd7c7e |
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