ZNF506-dependent positive feedback loop regulates H2AX signaling after DNA damage

ZNF506-dependent positive feedback loop regulates H2AX signaling after DNA damage

Following double-strand break a cascade of events leads to the recruitment of repair factors to damaged sites. Here the authors identify ZNF506 as a key factor that mediates post-translational modification changes in H2AX affecting the DNA damage response.

Saved in:
Bibliographic Details
Main Authors: Somaira Nowsheen, Khaled Aziz, Kuntian Luo, Min Deng, Bo Qin, Jian Yuan, Karthik B. Jeganathan, Jia Yu, Henan Zhang, Wei Ding, Jan M. van Deursen, Zhenkun Lou
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Science
Q
Online Access:https://doaj.org/article/900eef9ab9884019ae8190fe48d02ee3
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/900eef9ab9884019ae8190fe48d02ee3

Similar Items