Akt mediates metastasis-associated gene 1 (MTA1) regulating the expression of E-cadherin and promoting the invasiveness of prostate cancer cells.

Human metastasis-associated gene 1 (MTA1) is highly associated with the metastasis of prostate cancer; however, the molecular functions of MTA1 that facilitate metastasis remain unclear. In this study, we demonstrate that the silencing of MTA1 by siRNA treatment results in the upregulation of E-cadh...

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Autores principales: Hongyan Wang, Liangsheng Fan, Juncheng Wei, Yanjie Weng, Li Zhou, Ying Shi, Wenjuan Zhou, Ding Ma, Changyu Wang
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/9013904d69cd4932ba77490f17698838
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