Akt mediates metastasis-associated gene 1 (MTA1) regulating the expression of E-cadherin and promoting the invasiveness of prostate cancer cells.
Human metastasis-associated gene 1 (MTA1) is highly associated with the metastasis of prostate cancer; however, the molecular functions of MTA1 that facilitate metastasis remain unclear. In this study, we demonstrate that the silencing of MTA1 by siRNA treatment results in the upregulation of E-cadh...
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Autores principales: | Hongyan Wang, Liangsheng Fan, Juncheng Wei, Yanjie Weng, Li Zhou, Ying Shi, Wenjuan Zhou, Ding Ma, Changyu Wang |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/9013904d69cd4932ba77490f17698838 |
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