Prospective validation of an 11-gene mRNA host response score for mortality risk stratification in the intensive care unit

Prospective validation of an 11-gene mRNA host response score for mortality risk stratification in the intensive care unit

Abstract Several clinical calculators predict intensive care unit (ICU) mortality, however these are cumbersome and often require 24 h of data to calculate. Retrospective studies have demonstrated the utility of whole blood transcriptomic analysis in predicting mortality. In this study, we tested pr...

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Main Authors: Andrew R. Moore, Jonasel Roque, Brian T. Shaller, Tola Asuni, Melissa Remmel, David Rawling, Oliver Liesenfeld, Purvesh Khatri, Jennifer G. Wilson, Joseph E. Levitt, Timothy E. Sweeney, Angela J. Rogers
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/9016b66e9dfe42e596b816afde6595da
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https://doaj.org/article/9016b66e9dfe42e596b816afde6595da

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