Ten years of pathway analysis: current approaches and outstanding challenges.

por Purvesh Khatri, Marina Sirota, Atul J Butte
Publicado 2012

Leveraging heterogeneity across multiple datasets increases cell-mixture deconvolution accuracy and reduces biological and technical biases

por Francesco Vallania, Andrew Tam, Shane Lofgren, Steven Schaffert, Tej D. Azad, Erika Bongen, Winston Haynes, Meia Alsup, Michael Alonso, Mark Davis, Edgar Engleman, Purvesh Khatri
Publicado 2018

Interpretation of biological experiments changes with evolution of the Gene Ontology and its annotations

por Aurelie Tomczak, Jonathan M. Mortensen, Rainer Winnenburg, Charles Liu, Dominique T. Alessi, Varsha Swamy, Francesco Vallania, Shane Lofgren, Winston Haynes, Nigam H. Shah, Mark A. Musen, Purvesh Khatri
Publicado 2018

Prospective validation of an 11-gene mRNA host response score for mortality risk stratification in the intensive care unit

por Andrew R. Moore, Jonasel Roque, Brian T. Shaller, Tola Asuni, Melissa Remmel, David Rawling, Oliver Liesenfeld, Purvesh Khatri, Jennifer G. Wilson, Joseph E. Levitt, Timothy E. Sweeney, Angela J. Rogers
Publicado 2021

A generalizable 29-mRNA neural-network classifier for acute bacterial and viral infections

por Michael B. Mayhew, Ljubomir Buturovic, Roland Luethy, Uros Midic, Andrew R. Moore, Jonasel A. Roque, Brian D. Shaller, Tola Asuni, David Rawling, Melissa Remmel, Kirindi Choi, James Wacker, Purvesh Khatri, Angela J. Rogers, Timothy E. Sweeney
Publicado 2020

An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer

por Adrian Vallejo, Naiara Perurena, Elisabet Guruceaga, Pawel K. Mazur, Susana Martinez-Canarias, Carolina Zandueta, Karmele Valencia, Andrea Arricibita, Dana Gwinn, Leanne C. Sayles, Chen-Hua Chuang, Laura Guembe, Peter Bailey, David K. Chang, Andrew Biankin, Mariano Ponz-Sarvise, Jesper B. Andersen, Purvesh Khatri, Aline Bozec, E. Alejandro Sweet-Cordero, Julien Sage, Fernando Lecanda, Silve Vicent
Publicado 2017

A community approach to mortality prediction in sepsis via gene expression analysis

por Timothy E. Sweeney, Thanneer M. Perumal, Ricardo Henao, Marshall Nichols, Judith A. Howrylak, Augustine M. Choi, Jesús F. Bermejo-Martin, Raquel Almansa, Eduardo Tamayo, Emma E. Davenport, Katie L. Burnham, Charles J. Hinds, Julian C. Knight, Christopher W. Woods, Stephen F. Kingsmore, Geoffrey S. Ginsburg, Hector R. Wong, Grant P. Parnell, Benjamin Tang, Lyle L. Moldawer, Frederick E. Moore, Larsson Omberg, Purvesh Khatri, Ephraim L. Tsalik, Lara M. Mangravite, Raymond J. Langley
Publicado 2018