Rapid and improved oral absorption of N-butylphthalide by sodium cholate-appended liposomes for efficient ischemic stroke therapy

As a multi-target drug to treat ischemic stroke, N-butylphthalide (NBP) is extremely water-insoluble and exhibits limited oral bioavailability, impeding its wide oral application. Effective treatment of ischemic stroke by NBP requires timely and efficient drug exposure, necessitating the development...

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Auteurs principaux: Ailing Zhang, Jianbo Li, Shuaishuai Wang, Yaru Xu, Qinglian Li, Zhe Wu, Chenxu Wang, Haiyang Meng, Jinjie Zhang
Format: article
Langue:EN
Publié: Taylor & Francis Group 2021
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Accès en ligne:https://doaj.org/article/90acf7aac0654f6b982a7a7cae89fb53
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