Heat shock transcription factor 1-deficiency attenuates overloading-associated hypertrophy of mouse soleus muscle.

Heat shock transcription factor 1-deficiency attenuates overloading-associated hypertrophy of mouse soleus muscle.

Hypertrophic stimuli, such as mechanical stress and overloading, induce stress response, which is mediated by heat shock transcription factor 1 (HSF1), and up-regulate heat shock proteins (HSPs) in mammalian skeletal muscles. Therefore, HSF1-associated stress response may play a key role in loading-...

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Main Authors: Tomoyuki Koya, Sono Nishizawa, Yoshitaka Ohno, Ayumi Goto, Akihiro Ikuta, Miho Suzuki, Tomotaka Ohira, Tatsuro Egawa, Akira Nakai, Takao Sugiura, Yoshinobu Ohira, Toshitada Yoshioka, Moroe Beppu, Katsumasa Goto
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/90b32974e9c94f95ac18ac62a1c1899d
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https://doaj.org/article/90b32974e9c94f95ac18ac62a1c1899d

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