In vitro ribosome synthesis and evolution through ribosome display

Directed evolution of the ribosome is challenging because the requirement of cell viability limits the mutations that can be made. Here the authors develop a platform for in vitro ribosome synthesis and evolution (RISE) to overcome these constraints.

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Autores principales: Michael J. Hammerling, Brian R. Fritz, Danielle J. Yoesep, Do Soon Kim, Erik D. Carlson, Michael C. Jewett
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/90c6cf26ca364bed8ba59a292847a428
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