Liposomal Nanocarriers Designed for Sub-Endothelial Matrix Targeting under Vascular Flow Conditions

Liposomal Nanocarriers Designed for Sub-Endothelial Matrix Targeting under Vascular Flow Conditions

Vascular interventions result in the disruption of the tunica intima and the exposure of sub-endothelial matrix proteins. Nanoparticles designed to bind to these exposed matrices could provide targeted drug delivery systems aimed at inhibiting dysfunctional vascular remodeling and improving interven...

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Bibliographic Details
Main Authors: Lauren B. Grimsley, Phillip C. West, Callie D. McAdams, Charles A. Bush, Stacy S. Kirkpatrick, Joshua D. Arnold, Michael R. Buckley, Raymond A. Dieter, Michael B. Freeman, Michael M. McNally, Scott L. Stevens, Oscar H. Grandas, Deidra J. H. Mountain
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
liposomes
targeted drug delivery
hemodynamic flow
vascular shear stress
vascular therapeutics
Pharmacy and materia medica
RS1-441
Online Access:https://doaj.org/article/90e4197913bc4138b5ab94f8e72b3c32
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https://doaj.org/article/90e4197913bc4138b5ab94f8e72b3c32

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