Lack of AcrB Efflux Function Confers Loss of Virulence on <italic toggle="yes">Salmonella enterica</italic> Serovar Typhimurium

Lack of AcrB Efflux Function Confers Loss of Virulence on <italic toggle="yes">Salmonella enterica</italic> Serovar Typhimurium

ABSTRACT AcrAB-TolC is the paradigm resistance-nodulation-division (RND) multidrug resistance efflux system in Gram-negative bacteria, with AcrB being the pump protein in this complex. We constructed a nonfunctional AcrB mutant by replacing D408, a highly conserved residue essential for proton trans...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Xuan Wang-Kan, Jessica M. A. Blair, Barbara Chirullo, Jonathan Betts, Roberto M. La Ragione, Alasdair Ivens, Vito Ricci, Timothy J. Opperman, Laura J. V. Piddock
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2017
Materias:
AcrB
SPI
Salmonella
Salmonella pathogenicity island
efflux
motility
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/91114a33f62a45c7933725d7402ec642
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares