Clinically Relevant Mutant DNA Gyrase Alters Supercoiling, Changes the Transcriptome, and Confers Multidrug Resistance

por Mark A. Webber, Vito Ricci, Rebekah Whitehead, Meha Patel, Maria Fookes, Alasdair Ivens, Laura J. V. Piddock
Publicado 2013

Metabolomics Reveal Potential Natural Substrates of AcrB in Escherichia coli and Salmonella enterica Serovar Typhimurium

por Xuan Wang-Kan, Giovanny Rodríguez-Blanco, Andrew D. Southam, Catherine L. Winder, Warwick B. Dunn, Alasdair Ivens, Laura J. V. Piddock
Publicado 2021

Beyond Antimicrobial Resistance: Evidence for a Distinct Role of the AcrD Efflux Pump in <italic toggle="yes">Salmonella</italic> Biology

por Michelle M. C. Buckner, Jessica M. A. Blair, Roberto M. La Ragione, Jane Newcombe, Daniel J. Dwyer, Alasdair Ivens, Laura J. V. Piddock
Publicado 2016

Lack of AcrB Efflux Function Confers Loss of Virulence on <italic toggle="yes">Salmonella enterica</italic> Serovar Typhimurium

por Xuan Wang-Kan, Jessica M. A. Blair, Barbara Chirullo, Jonathan Betts, Roberto M. La Ragione, Alasdair Ivens, Vito Ricci, Timothy J. Opperman, Laura J. V. Piddock
Publicado 2017

Chlorpromazine and Amitriptyline Are Substrates and Inhibitors of the AcrB Multidrug Efflux Pump

por Elizabeth M. Grimsey, Chiara Fais, Robert L. Marshall, Vito Ricci, Maria Laura Ciusa, Jack W. Stone, Alasdair Ivens, Giuliano Malloci, Paolo Ruggerone, Attilio V. Vargiu, Laura J. V. Piddock
Publicado 2020

Clinically Relevant Plasmid-Host Interactions Indicate that Transcriptional and Not Genomic Modifications Ameliorate Fitness Costs of <italic toggle="yes">Klebsiella pneumoniae</it...

por Michelle M. C. Buckner, Howard T. H. Saw, Rachael N. Osagie, Alan McNally, Vito Ricci, Matthew E. Wand, Neil Woodford, Alasdair Ivens, Mark A. Webber, Laura J. V. Piddock
Publicado 2018

Erratum for Richmond et al., The <named-content content-type="genus-species">Acinetobacter baumannii</named-content> Two-Component System AdeRS Regulates Genes Required for Multidr...

por Grace E. Richmond, Laura P. Evans, Michele J. Anderson, Matthew E. Wand, Laura C. Bonney, Alasdair Ivens, Kim Lee Chua, Mark A. Webber, J. Mark Sutton, Marnie L. Peterson, Laura J. V. Piddock
Publicado 2016

The <named-content content-type="genus-species">Acinetobacter baumannii</named-content> Two-Component System AdeRS Regulates Genes Required for Multidrug Efflux, Biofilm Formation,...

por Grace E. Richmond, Laura P. Evans, Michele J. Anderson, Matthew E. Wand, Laura C. Bonney, Alasdair Ivens, Kim Lee Chua, Mark A. Webber, J. Mark Sutton, Marnie L. Peterson, Laura J. V. Piddock
Publicado 2016

Sir2 paralogues cooperate to regulate virulence genes and antigenic variation in Plasmodium falciparum.

por Christopher J Tonkin, Céline K Carret, Manoj T Duraisingh, Till S Voss, Stuart A Ralph, Mirja Hommel, Michael F Duffy, Liliana Mancio da Silva, Artur Scherf, Alasdair Ivens, Terence P Speed, James G Beeson, Alan F Cowman
Publicado 2009

A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells

por Chris J. C. Johnston, Danielle J. Smyth, Ravindra B. Kodali, Madeleine P. J. White, Yvonne Harcus, Kara J. Filbey, James P. Hewitson, Cynthia S. Hinck, Alasdair Ivens, Andrea M. Kemter, Anna O. Kildemoes, Thierry Le Bihan, Dinesh C. Soares, Stephen M. Anderton, Thomas Brenn, Stephen J. Wigmore, Hannah V. Woodcock, Rachel C. Chambers, Andrew P. Hinck, Henry J. McSorley, Rick M. Maizels
Publicado 2017