Functional rotation of the transporter AcrB: insights into drug extrusion from simulations.

par Robert Schulz, Attilio V Vargiu, Francesca Collu, Ulrich Kleinekathöfer, Paolo Ruggerone
Publié 2010

Molecular Rationale behind the Differential Substrate Specificity of Bacterial RND Multi-Drug Transporters

par Venkata Krishnan Ramaswamy, Attilio V. Vargiu, Giuliano Malloci, Jürg Dreier, Paolo Ruggerone
Publié 2017

Chlorpromazine and Amitriptyline Are Substrates and Inhibitors of the AcrB Multidrug Efflux Pump

par Elizabeth M. Grimsey, Chiara Fais, Robert L. Marshall, Vito Ricci, Maria Laura Ciusa, Jack W. Stone, Alasdair Ivens, Giuliano Malloci, Paolo Ruggerone, Attilio V. Vargiu, Laura J. V. Piddock
Publié 2020

Perturbed structural dynamics underlie inhibition and altered efflux of the multidrug resistance pump AcrB

par Eamonn Reading, Zainab Ahdash, Chiara Fais, Vito Ricci, Xuan Wang-Kan, Elizabeth Grimsey, Jack Stone, Giuliano Malloci, Andy M. Lau, Heather Findlay, Albert Konijnenberg, Paula J. Booth, Paolo Ruggerone, Attilio V. Vargiu, Laura J. V. Piddock, Argyris Politis
Publié 2020

Predictive Rules of Efflux Inhibition and Avoidance in Pseudomonas aeruginosa

par Jitender Mehla, Giuliano Malloci, Rachael Mansbach, Cesar A. López, Ruslan Tsivkovski, Keith Haynes, Inga V. Leus, Sally B. Grindstaff, Robert H. Cascella, Napoleon D’Cunha, Liam Herndon, Nicolas W. Hengartner, Enrico Margiotta, Alessio Atzori, Attilio V. Vargiu, Pedro D. Manrique, John K. Walker, Olga Lomovskaya, Paolo Ruggerone, S. Gnanakaran, Valentin V. Rybenkov, Helen I. Zgurskaya
Publié 2021