Evidence that the <named-content content-type="genus-species">Plasmodium falciparum</named-content> Protein Sortilin Potentially Acts as an Escorter for the Trafficking of the Rhop...

por Stéphanie Hallée, Justin A. Boddey, Alan F. Cowman, Dave Richard
Publicado 2018

Protein Kinase A Is Essential for Invasion of <named-content content-type="genus-species">Plasmodium falciparum</named-content> into Human Erythrocytes

por Mary-Louise Wilde, Tony Triglia, Danushka Marapana, Jennifer K. Thompson, Alexei A. Kouzmitchev, Hayley E. Bullen, Paul R. Gilson, Alan F. Cowman, Christopher J. Tonkin
Publicado 2019

An EGF-like protein forms a complex with PfRh5 and is required for invasion of human erythrocytes by Plasmodium falciparum.

por Lin Chen, Sash Lopaticki, David T Riglar, Chaitali Dekiwadia, Alex D Uboldi, Wai-Hong Tham, Matthew T O'Neill, Dave Richard, Jake Baum, Stuart A Ralph, Alan F Cowman
Publicado 2011

Plasmodium falciparum heterochromatin protein 1 marks genomic loci linked to phenotypic variation of exported virulence factors.

por Christian Flueck, Richard Bartfai, Jennifer Volz, Igor Niederwieser, Adriana M Salcedo-Amaya, Blaise T F Alako, Florian Ehlgen, Stuart A Ralph, Alan F Cowman, Zbynek Bozdech, Hendrik G Stunnenberg, Till S Voss
Publicado 2009

The Metabolite Repair Enzyme Phosphoglycolate Phosphatase Regulates Central Carbon Metabolism and Fosmidomycin Sensitivity in <named-content content-type="genus-species">Plasmodium...

por Laure Dumont, Mark B. Richardson, Phillip van der Peet, Danushka S. Marapana, Tony Triglia, Matthew W. A. Dixon, Alan F. Cowman, Spencer J. Williams, Leann Tilley, Malcolm J. McConville, Simon A. Cobbold
Publicado 2019

4D analysis of malaria parasite invasion offers insights into erythrocyte membrane remodeling and parasitophorous vacuole formation

por Niall D. Geoghegan, Cindy Evelyn, Lachlan W. Whitehead, Michal Pasternak, Phoebe McDonald, Tony Triglia, Danushka S. Marapana, Daryan Kempe, Jennifer K. Thompson, Michael J. Mlodzianoski, Julie Healer, Maté Biro, Alan F. Cowman, Kelly L. Rogers
Publicado 2021

Sir2 paralogues cooperate to regulate virulence genes and antigenic variation in Plasmodium falciparum.

por Christopher J Tonkin, Céline K Carret, Manoj T Duraisingh, Till S Voss, Stuart A Ralph, Mirja Hommel, Michael F Duffy, Liliana Mancio da Silva, Artur Scherf, Alasdair Ivens, Terence P Speed, James G Beeson, Alan F Cowman
Publicado 2009

Export of malaria proteins requires co-translational processing of the PEXEL motif independent of phosphatidylinositol-3-phosphate binding

por Justin A. Boddey, Matthew T. O’Neill, Sash Lopaticki, Teresa G. Carvalho, Anthony N. Hodder, Thomas Nebl, Stephan Wawra, Pieter van West, Zeinab Ebrahimzadeh, Dave Richard, Sven Flemming, Tobias Spielmann, Jude Przyborski, Jeff J. Babon, Alan F. Cowman
Publicado 2016

Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites.

por Brad E Sleebs, Sash Lopaticki, Danushka S Marapana, Matthew T O'Neill, Pravin Rajasekaran, Michelle Gazdik, Svenja Günther, Lachlan W Whitehead, Kym N Lowes, Lea Barfod, Lars Hviid, Philip J Shaw, Anthony N Hodder, Brian J Smith, Alan F Cowman, Justin A Boddey
Publicado 2014

Spatial localisation of actin filaments across developmental stages of the malaria parasite.

por Fiona Angrisano, David T Riglar, Angelika Sturm, Jennifer C Volz, Michael J Delves, Elizabeth S Zuccala, Lynne Turnbull, Chaitali Dekiwadia, Maya A Olshina, Danushka S Marapana, Wilson Wong, Vanessa Mollard, Clare H Bradin, Christopher J Tonkin, Peter W Gunning, Stuart A Ralph, Cynthia B Whitchurch, Robert E Sinden, Alan F Cowman, Geoffrey I McFadden, Jake Baum
Publicado 2012

Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway

por Gregory M. LaMonte, Frances Rocamora, Danushka S. Marapana, Nina F. Gnädig, Sabine Ottilie, Madeline R. Luth, Tilla S. Worgall, Gregory M. Goldgof, Roxanne Mohunlal, T. R. Santha Kumar, Jennifer K. Thompson, Edgar Vigil, Jennifer Yang, Dylan Hutson, Trevor Johnson, Jianbo Huang, Roy M. Williams, Bing Yu Zou, Andrea L. Cheung, Prianka Kumar, Timothy J. Egan, Marcus C. S. Lee, Dionicio Siegel, Alan F. Cowman, David A. Fidock, Elizabeth A. Winzeler
Publicado 2020

Safety, infectivity and immunogenicity of a genetically attenuated blood-stage malaria vaccine

por Rebecca Webster, Silvana Sekuloski, Anand Odedra, Stephen Woolley, Helen Jennings, Fiona Amante, Katharine R. Trenholme, Julie Healer, Alan F. Cowman, Emily M. Eriksson, Priyanka Sathe, Jocelyn Penington, Adam J. Blanch, Matthew W. A. Dixon, Leann Tilley, Michael F. Duffy, Alister Craig, Janet Storm, Jo-Anne Chan, Krystal Evans, Anthony T. Papenfuss, Louis Schofield, Paul Griffin, Bridget E. Barber, Dean Andrew, Michelle J. Boyle, Fabian de Labastida Rivera, Christian Engwerda, James S. McCarthy
Publicado 2021