The Key Glycolytic Enzyme Phosphofructokinase Is Involved in Resistance to Antiplasmodial Glycosides

por Gillian M. Fisher, Simon A. Cobbold, Andrew Jezewski, Emma F. Carpenter, Megan Arnold, Annie N. Cowell, Erick T. Tjhin, Kevin J. Saliba, Tina S. Skinner-Adams, Marcus C. S. Lee, Audrey Odom John, Elizabeth A. Winzeler, Malcolm J. McConville, Sally-Ann Poulsen, Katherine T. Andrews
Publicado 2020

A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue

por Ebere Sonoiki, Caroline L. Ng, Marcus C. S. Lee, Denghui Guo, Yong-Kang Zhang, Yasheen Zhou, M. R. K. Alley, Vida Ahyong, Laura M. Sanz, Maria Jose Lafuente-Monasterio, Chen Dong, Patrick G. Schupp, Jiri Gut, Jenny Legac, Roland A. Cooper, Francisco-Javier Gamo, Joseph DeRisi, Yvonne R. Freund, David A. Fidock, Philip J. Rosenthal
Publicado 2017

Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway

por Gregory M. LaMonte, Frances Rocamora, Danushka S. Marapana, Nina F. Gnädig, Sabine Ottilie, Madeline R. Luth, Tilla S. Worgall, Gregory M. Goldgof, Roxanne Mohunlal, T. R. Santha Kumar, Jennifer K. Thompson, Edgar Vigil, Jennifer Yang, Dylan Hutson, Trevor Johnson, Jianbo Huang, Roy M. Williams, Bing Yu Zou, Andrea L. Cheung, Prianka Kumar, Timothy J. Egan, Marcus C. S. Lee, Dionicio Siegel, Alan F. Cowman, David A. Fidock, Elizabeth A. Winzeler
Publicado 2020

A broad analysis of resistance development in the malaria parasite

por Victoria C. Corey, Amanda K. Lukens, Eva S. Istvan, Marcus C. S. Lee, Virginia Franco, Pamela Magistrado, Olivia Coburn-Flynn, Tomoyo Sakata-Kato, Olivia Fuchs, Nina F. Gnädig, Greg Goldgof, Maria Linares, Maria G. Gomez-Lorenzo, Cristina De Cózar, Maria Jose Lafuente-Monasterio, Sara Prats, Stephan Meister, Olga Tanaseichuk, Melanie Wree, Yingyao Zhou, Paul A. Willis, Francisco-Javier Gamo, Daniel E. Goldberg, David A. Fidock, Dyann F. Wirth, Elizabeth A. Winzeler
Publicado 2016