Gain-of-Function Mutations in the Phospholipid Flippase MprF Confer Specific Daptomycin Resistance
ABSTRACT Daptomycin, a calcium-dependent lipopeptide antibiotic whose full mode of action is still not entirely understood, has become a standard-of-care agent for treating methicillin-resistant Staphylococcus aureus (MRSA) infections. Daptomycin-resistant (DAP-R) S. aureus mutants emerge during the...
Enregistré dans:
Auteurs principaux: | , , , , , , , , |
---|---|
Format: | article |
Langue: | EN |
Publié: |
American Society for Microbiology
2018
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/91185988fd2b4f0eadcc6a36be94023e |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|