Curcumin promotes A-beta fibrillation and reduces neurotoxicity in transgenic Drosophila.

The pathology of Alzheimer's disease (AD) is characterized by the presence of extracellular deposits of misfolded and aggregated amyloid-β (Aβ) peptide and intraneuronal accumulation of tangles comprised of hyperphosphorylated Tau protein. For several years, the natural compound curcumin has be...

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Autores principales: Ina Caesar, Maria Jonson, K Peter R Nilsson, Stefan Thor, Per Hammarström
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/911ddf1bf50e46d883d390f377823301
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