Raptor determines β-cell identity and plasticity independent of hyperglycemia in mice

During the progression of type 2 diabetes, insulin-producing β-cells can lose their identity and become reprogrammed into other cell types. Here the authors show that murine diabetic β-cells require the protein Raptor for maintaining β-cell health and preventing them from turning into α-cells, indep...

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Auteurs principaux: Qinglei Yin, Qicheng Ni, Yichen Wang, Hongli Zhang, Wenyi Li, Aifang Nie, Shu Wang, Yanyun Gu, Qidi Wang, Guang Ning
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/912693f29da74215989426c806a40972
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