Raptor determines β-cell identity and plasticity independent of hyperglycemia in mice
During the progression of type 2 diabetes, insulin-producing β-cells can lose their identity and become reprogrammed into other cell types. Here the authors show that murine diabetic β-cells require the protein Raptor for maintaining β-cell health and preventing them from turning into α-cells, indep...
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| Auteurs principaux: | Qinglei Yin, Qicheng Ni, Yichen Wang, Hongli Zhang, Wenyi Li, Aifang Nie, Shu Wang, Yanyun Gu, Qidi Wang, Guang Ning |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2020
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/912693f29da74215989426c806a40972 |
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