Raptor determines β-cell identity and plasticity independent of hyperglycemia in mice
During the progression of type 2 diabetes, insulin-producing β-cells can lose their identity and become reprogrammed into other cell types. Here the authors show that murine diabetic β-cells require the protein Raptor for maintaining β-cell health and preventing them from turning into α-cells, indep...
        Guardado en:
      
    
                  | Autores principales: | Qinglei Yin, Qicheng Ni, Yichen Wang, Hongli Zhang, Wenyi Li, Aifang Nie, Shu Wang, Yanyun Gu, Qidi Wang, Guang Ning | 
|---|---|
| Formato: | article | 
| Lenguaje: | EN | 
| Publicado: | 
        
      Nature Portfolio    
    
      2020
     | 
| Materias: | |
| Acceso en línea: | https://doaj.org/article/912693f29da74215989426c806a40972 | 
| Etiquetas: | 
       Agregar Etiqueta    
     
      Sin Etiquetas, Sea el primero en etiquetar este registro!
   
 | 
Ejemplares similares
- 
                
        
          Raptor regulates functional maturation of murine beta cells        
                  
por: Qicheng Ni, et al.
Publicado: (2017) - 
                
        
          Autophagy in muscle of glucose-infusion hyperglycemia rats and streptozotocin-induced hyperglycemia rats via selective activation of m-TOR or FoxO3.        
                  
por: Pengfei Lv, et al.
Publicado: (2014) - 
                
        
          mTORC1-independent Raptor prevents hepatic steatosis by stabilizing PHLPP2        
                  
por: KyeongJin Kim, et al.
Publicado: (2016) - Slovak raptor journal
 - 
                
        
          The Journal of raptor research        
                          
Publicado: (1987)