Roles for the 8-Oxoguanine DNA Repair System in Protecting Telomeres From Oxidative Stress

Telomeres are protective nucleoprotein structures that cap linear chromosome ends and safeguard genome stability. Progressive telomere shortening at each somatic cell division eventually leads to critically short and dysfunctional telomeres, which can contribute to either cellular senescence and agi...

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Bibliographic Details
Main Authors: Mariarosaria De Rosa, Samuel A. Johnson, Patricia L. Opresko
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
Online Access:https://doaj.org/article/912a1ffc65cb4bdba2c68957eb4daf07
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