Auxin‐mediated induction of GAL promoters by conditional degradation of Mig1p improves sesquiterpene production in Saccharomyces cerevisiae with engineered acetyl‐CoA synthesis

Summary The yeast Saccharomyces cerevisiae uses the pyruvate dehydrogenase‐bypass for acetyl‐CoA biosynthesis. This relatively inefficient pathway limits production potential for acetyl‐CoA‐derived biochemical due to carbon loss and the cost of two high‐energy phosphate bonds per molecule of acetyl‐...

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Auteurs principaux: Irfan Farabi Hayat, Manuel Plan, Birgitta E. Ebert, Geoff Dumsday, Claudia E. Vickers, Bingyin Peng
Format: article
Langue:EN
Publié: Wiley 2021
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Accès en ligne:https://doaj.org/article/912b849ae4dd4eeab30401b22a5f7992
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