She1 affects dynein through direct interactions with the microtubule and the dynein microtubule-binding domain

Dynein is a microtubule motor the motility of which is affected by the microtubule-associated protein She1. Here, the authors show that She1 alters dynein stepping behavior and increases its microtubule affinity through simultaneous interactions with the microtubule and dynein microtubule binding do...

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Auteurs principaux: Kari H. Ecklund, Tatsuya Morisaki, Lindsay G. Lammers, Matthew G. Marzo, Timothy J. Stasevich, Steven M. Markus
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/913bdefabfaa49f98b3f7aa602394933
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