Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation

Tailed bacteriophages assemble empty precursor capsids known as procapsids that are subsequently filled with viral DNA by a genome-packaging motor. Here the authors present a structure-based analysis that suggests the signal for termination of genome packaging is achieved through a DNA-dependent sym...

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Bibliographic Details
Main Authors: Ravi K. Lokareddy, Rajeshwer S. Sankhala, Ankoor Roy, Pavel V. Afonine, Tina Motwani, Carolyn M. Teschke, Kristin N. Parent, Gino Cingolani
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/9153c6cc3a8e422c89bc78e6f3ac607c
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