Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation

Tailed bacteriophages assemble empty precursor capsids known as procapsids that are subsequently filled with viral DNA by a genome-packaging motor. Here the authors present a structure-based analysis that suggests the signal for termination of genome packaging is achieved through a DNA-dependent sym...

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Autores principales:	Ravi K. Lokareddy, Rajeshwer S. Sankhala, Ankoor Roy, Pavel V. Afonine, Tina Motwani, Carolyn M. Teschke, Kristin N. Parent, Gino Cingolani
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9153c6cc3a8e422c89bc78e6f3ac607c
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spelling	oai:doaj.org-article:9153c6cc3a8e422c89bc78e6f3ac607c2021-12-02T15:36:59ZPortal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation10.1038/ncomms143102041-1723https://doaj.org/article/9153c6cc3a8e422c89bc78e6f3ac607c2017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms14310https://doaj.org/toc/2041-1723Tailed bacteriophages assemble empty precursor capsids known as procapsids that are subsequently filled with viral DNA by a genome-packaging motor. Here the authors present a structure-based analysis that suggests the signal for termination of genome packaging is achieved through a DNA-dependent symmetrization of portal protein.Ravi K. LokareddyRajeshwer S. SankhalaAnkoor RoyPavel V. AfonineTina MotwaniCarolyn M. TeschkeKristin N. ParentGino CingolaniNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ravi K. Lokareddy Rajeshwer S. Sankhala Ankoor Roy Pavel V. Afonine Tina Motwani Carolyn M. Teschke Kristin N. Parent Gino Cingolani Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation
description	Tailed bacteriophages assemble empty precursor capsids known as procapsids that are subsequently filled with viral DNA by a genome-packaging motor. Here the authors present a structure-based analysis that suggests the signal for termination of genome packaging is achieved through a DNA-dependent symmetrization of portal protein.
format	article
author	Ravi K. Lokareddy Rajeshwer S. Sankhala Ankoor Roy Pavel V. Afonine Tina Motwani Carolyn M. Teschke Kristin N. Parent Gino Cingolani
author_facet	Ravi K. Lokareddy Rajeshwer S. Sankhala Ankoor Roy Pavel V. Afonine Tina Motwani Carolyn M. Teschke Kristin N. Parent Gino Cingolani
author_sort	Ravi K. Lokareddy
title	Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation
title_short	Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation
title_full	Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation
title_fullStr	Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation
title_full_unstemmed	Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation
title_sort	portal protein functions akin to a dna-sensor that couples genome-packaging to icosahedral capsid maturation
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/9153c6cc3a8e422c89bc78e6f3ac607c
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Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation

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