A convolutional neural network for the prediction and forward design of ribozyme-based gene-control elements

Ribozyme switches are a class of RNA-encoded genetic switch that support conditional regulation of gene expression across diverse organisms. An improved elucidation of the relationships between sequence, structure, and activity can improve our capacity for de novo rational design of ribozyme switche...

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Auteurs principaux: Calvin M Schmidt, Christina D Smolke
Format: article
Langue:EN
Publié: eLife Sciences Publications Ltd 2021
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/915fab600fbe453a9bab9db65ba07394
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