A Cytoplasmic Heme Sensor Illuminates the Impacts of Mitochondrial and Vacuolar Functions and Oxidative Stress on Heme-Iron Homeostasis in <named-content content-type="genus-species">Cryptococcus neoformans</named-content>
ABSTRACT Pathogens must compete with hosts to acquire sufficient iron for proliferation during pathogenesis. The pathogenic fungus Cryptococcus neoformans is capable of acquiring iron from heme, the most abundant source in vertebrate hosts, although the mechanisms of heme sensing and acquisition are...
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| Format: | article |
| Langue: | EN |
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American Society for Microbiology
2020
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| Accès en ligne: | https://doaj.org/article/9169079d309340e5ae58f60ddcd84590 |
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