Paraquat poisoning induces TNF-α-dependent iNOS/NO mediated hyporesponsiveness of the aorta to vasoconstrictors in rats.

Paraquat is a toxic herbicide that may induce acute lung injury, circulatory failure and death. The present work aimed at investigating whether there is systemic inflammation and vascular dysfunction after paraquat exposure and whether these parameters were related. There was neutrophilia and accumu...

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Autores principales: Rosária D Aires, Luciano S A Capettini, Josiane F Silva, Maria da Glória Rodrigues-Machado, Vanessa Pinho, Mauro M Teixeira, Steyner F Cortes, Virginia S Lemos
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/91c7d8fb75c544c3a9650dfa6f602922
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