CRISPR/Cas9 Genome Editing Reveals That the Intron Is Not Essential for <italic toggle="yes">var2csa</italic> Gene Activation or Silencing in <italic toggle="yes">Plasmodium falciparum</italic>
ABSTRACT Plasmodium falciparum relies on monoallelic expression of 1 of 60 var virulence genes for antigenic variation and host immune evasion. Each var gene contains a conserved intron which has been implicated in previous studies in both activation and repression of transcription via several epige...
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Main Authors: | , , , , , |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2017
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Subjects: | |
Online Access: | https://doaj.org/article/91d89e87606c4bb78714e1eb9743529d |
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