Stabilization of the classical phenotype upon integration of pancreatic cancer cells into the duodenal epithelium

Introduction: Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive solid tumors. Based on transcriptomic classifiers, basal-like and classical PDAC subtypes have been defined that differ in prognosis. Cells of both subtypes can coexist in individual tumors; however, the contribution...

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Main Authors: Benedek Bozóky, Carlos Fernández Moro, Carina Strell, Natalie Geyer, Rainer L. Heuchel, J. Matthias Löhr, Ingemar Ernberg, Laszlo Szekely, Marco Gerling, Béla Bozóky
Format: article
Language:EN
Published: Elsevier 2021
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Online Access:https://doaj.org/article/91e8e2b3c7e24a6e950edafe3ff950a1
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