Rotavirus increases levels of lipidated LC3 supporting accumulation of infectious progeny virus without inducing autophagosome formation.
Replication of many RNA viruses benefits from subversion of the autophagic pathway through many different mechanisms. Rotavirus, the main etiologic agent of pediatric gastroenteritis worldwide, has been recently described to induce accumulation of autophagosomes as a mean for targeting viral protein...
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Auteurs principaux: | Francesca Arnoldi, Giuditta De Lorenzo, Miguel Mano, Elisabeth M Schraner, Peter Wild, Catherine Eichwald, Oscar R Burrone |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2014
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Accès en ligne: | https://doaj.org/article/91f5ca427fab47bca2101ed0b9d2cdb2 |
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