DHAV-1 Blocks the Signaling Pathway Upstream of Type I Interferon by Inhibiting the Interferon Regulatory Factor 7 Protein

DHAV-1 Blocks the Signaling Pathway Upstream of Type I Interferon by Inhibiting the Interferon Regulatory Factor 7 Protein

Duck hepatitis A virus (DHAV), which mainly infects 1- to 4-week-old ducklings, has a fatality rate of 95% and poses a huge economic threat to the duck industry. However, the mechanism by which DHAV-1 regulates the immune response of host cells is rarely reported. This study examined whether DHAV-1...

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Autores principales: Yalan Lai, Xiaoyan Xia, Anchun Cheng, Mingshu Wang, Xumin Ou, Sai Mao, Di Sun, Shaqiu Zhang, Qiao Yang, Ying Wu, Dekang Zhu, Renyong Jia, Shun Chen, Mafeng Liu, Xin-Xin Zhao, Juan Huang, Qun Gao, Bin Tian, Yunya Liu, Yanling Yu, Ling Zhang, Leichang Pan
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
duck hepatitis A virus type I
3C protein
interferon regulatory factor 7
immune regulation
type I interferon
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/9217336816484fb998ce31655ff7b45b
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https://doaj.org/article/9217336816484fb998ce31655ff7b45b

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