In vivo human molecular neuroimaging of dopaminergic vulnerability along the Alzheimer’s disease phases

Abstract Background Preclinical and pathology evidence suggests an involvement of brain dopamine (DA) circuitry in Alzheimer’s disease (AD). We in vivo investigated if, when, and in which target regions [123I]FP-CIT-SPECT regional binding and molecular connectivity are damaged along the AD course. M...

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Autores principales:	Arianna Sala, Silvia Paola Caminiti, Luca Presotto, Andrea Pilotto, Claudio Liguori, Agostino Chiaravalloti, Valentina Garibotto, Giovanni Battista Frisoni, Marcello D’Amelio, Barbara Paghera, Orazio Schillaci, Nicola Mercuri, Alessandro Padovani, Daniela Perani
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Biomarker Dopamine Molecular connectivity Substantia nigra Ventral tegmental area Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/921d49dd07834f4fb2a6a1ada03cfd92
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In vivo human molecular neuroimaging of dopaminergic vulnerability along the Alzheimer’s disease phases

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