Ad-Apoptin-hTERTp-E1a Regulates Autophagy Through the AMPK-mTOR-eIF4F Signaling Axis to Reduce Drug Resistance of MCF-7/ADR Cells

Ad-VT (Ad-Apoptin-hTERTp-E1a) is a type of oncolytic adenovirus with dual specific tumor cell death ability. It can effectively induce cell death of breast cancer cells and has better effect when used in combination with chemotherapy drugs. However, it has not been reported whether Ad-VT reduces the...

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Autores principales: Yaru Li, Yilong Zhu, Jicheng Han, Jinbo Fang, Zhiru Xiu, Shanzhi Li, Wenjie Li, Xia Yang, Ningyi Jin, Lili Sun, Xiao Li, Yiquan Li
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/922dea3a9c7d4cb5aae5c856279421d5
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