mPEG-PLA/TPGS mixed micelles via intranasal administration improved the bioavailability of lamotrigine in the hippocampus

QR Code

mPEG-PLA/TPGS mixed micelles via intranasal administration improved the bioavailability of lamotrigine in the hippocampus

Anan Yu,1,* Jieqiong Lv,1,* Fang Yuan,1 Zihua Xia,1 Kaiyan Fan,1 Gang Chen,1,2 Jialin Ren,1 Cuicui Lin,1 Shijie Wei,1,2 Fan Yang1,2 1Department of Pharmaceutics, 2Guangdong Provincial Engineering Center of Topical Precise Drug Delivery System, Guangdong Pharmaceutical University, Guangzhou, Guangdo...

Description complète

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Yu A, Lv J, Yuan F, Xia Z, Fan K, Chen G, Ren J, Lin C, Wei S, Yang F
Format:	article
Langue:	EN
Publié:	Dove Medical Press 2017
Sujets:	Bioavailability epilepsy intranasal administration lamotrigine mixed micelle TPGS Medicine (General) R5-920
Accès en ligne:	https://doaj.org/article/923e727a12b840b6a08edf38485a8075
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires

Targeted delivery of ginsenoside compound K using TPGS/PEG-PCL mixed micelles for effective treatment of lung cancer
par: Yang L, et autres
Publié: (2017)

Encapsulating Halofuginone Hydrobromide in TPGS Polymeric Micelles Enhances Efficacy Against Triple-Negative Breast Cancer Cells
par: Zuo R, et autres
Publié: (2021)

Synthesis, characterization, and evaluation of mPEG–SN38 and mPEG–PLA–SN38 micelles for cancer therapy
par: Xie J, et autres
Publié: (2016)

Biodegradable mixed MPEG-SS-2SA/TPGS micelles for triggered intracellular release of paclitaxel and reversing multidrug resistance
par: Dong K, et autres
Publié: (2016)

Superiority of TPGS-loaded micelles in the brain delivery of vinpocetine via administration of thermosensitive intranasal gel
par: Ahmed TA, et autres
Publié: (2019)

DEVELOPMENT OF A SIMPLE LC METHOD FOR QUANTIFICATION OF LAMOTRIGINE IN HUMAN SERUM
par: Albornoz P.,M., et autres
Publié: (2020)

Lamotrigine Induced DRESS Syndrome in a Child: A Case Report and Literature Review
par: Chien-Heng Lin, et autres
Publié: (2021)

Development of a Solid Supersaturable Micelle of Revaprazan for Improved Dissolution and Oral Bioavailability Using Box-Behnken Design
par: Goo YT, et autres
Publié: (2021)

Combined administration of PTX and S-HM-3 in TPGS/Solutol micelle system for oncotarget therapy
par: Li W, et autres
Publié: (2019)

Folic acid-functionalized drug delivery platform of resveratrol based on Pluronic 127/D-α-tocopheryl polyethylene glycol 1000 succinate mixed micelles
par: Hao J, et autres
Publié: (2017)

3,5,4′-trimethoxy-trans-stilbene loaded PEG-PE micelles for the treatment of colon cancer
par: Wu JY, et autres
Publié: (2019)

Enhancing the oral bioavailability of biochanin A by encapsulation in mixed micelles containing Pluronic F127 and Plasdone S630
par: Wu X, et autres
Publié: (2017)

Transferrin Receptor-Targeted PEG-PLA Polymeric Micelles for Chemotherapy Against Glioblastoma Multiforme
par: Sun P, et autres
Publié: (2020)

Ascorbyl palmitate/d-α-tocopheryl polyethylene glycol 1000 succinate monoester mixed micelles for prolonged circulation and targeted delivery of compound K for antilung cancer therapy in vitro and in vivo
par: Zhang Y, et autres
Publié: (2017)

D-α-Tocopheryl polyethylene glycol succinate/Solutol HS 15 mixed micelles for the delivery of baohuoside I against non-small-cell lung cancer: optimization and in vitro, in vivo evaluation
par: Yan H, et autres
Publié: (2016)

Formulation and evaluation of mixed polymeric micelles of quercetin for treatment of breast, ovarian, and multidrug resistant cancers
par: Patra A, et autres
Publié: (2018)

Targeted delivery by pH-responsive mPEG-S-PBLG micelles significantly enhances the anti-tumor efficacy of doxorubicin with reduced cardiotoxicity
par: Qiyi Feng, et autres
Publié: (2021)

pH-sensitive and folic acid-targeted MPEG-PHIS/FA-PEG-VE mixed micelles for the delivery of PTX-VE and their antitumor activity
par: Di Y, et autres
Publié: (2017)

Lamotrigine‐induced neutropenia after high‐dose concomitant initiation with phenytoin
par: Muhammad Salem, et autres
Publié: (2021)

Development and evaluation of vitamin E D-α-tocopheryl polyethylene glycol 1000 succinate-mixed polymeric phospholipid micelles of berberine as an anticancer nanopharmaceutical
par: Shen R, et autres
Publié: (2016)

Escitalopram, bupropion, lurasidone, lamotrigine and possible vortioxetine overdose presented with serotonin syndrome and diffuse encephalopathy: A case report
par: Suthimon Thumtecho, et autres
Publié: (2021)

Mixed micelles loaded with the 5-benzylidenethiazolidine-2,4-dione derivative SKLB023 for efficient treatment of non-alcoholic steatohepatitis
par: Li Y, et autres
Publié: (2019)

TPGS-Modified Long-Circulating Liposomes Loading Ziyuglycoside I for Enhanced Therapy of Myelosuppression
par: Song T, et autres
Publié: (2021)

Intranasal delivery of rotigotine to the brain with lactoferrin-modified PEG-PLGA nanoparticles for Parkinson’s disease treatment
par: Bi CC, et autres
Publié: (2016)

Formulación de metoclopramida en partículas poliméricas mucoadhesivas para administración intranasal
par: Vargas-Fresneda,Marcela, et autres
Publié: (2020)

Synergistic apoptotic effects of apigenin TPGS liposomes and tyroservatide: implications for effective treatment of lung cancer
par: Jin X, et autres
Publié: (2017)

Reversed phase HPLC determination of zidovudine in rat plasma and its pharmacokinetics after a single intranasal dose administration
par: MAINARDES,RUBIANA M, et autres
Publié: (2009)

Long-term efficacy and safety of lamotrigine for all types of bipolar disorder
par: Watanabe Y, et autres
Publié: (2017)

Nefritis intersticial aguda y lamotrigina: Report of one case
par: Mönckeberg F,Gustavo, et autres
Publié: (2004)

Intranasal Delivery of miR-155-5p Antagomir Alleviates Acute Seizures Likely by Inhibiting Hippocampal Inflammation
par: Zhou X, et autres
Publié: (2020)

OPTIMIZING THE STRUCTURE OF AMPHIPHILIC INVERTIBLE POLYMERS (AIPs) MADE OF PEGs AND FATTY COMPOUND SEGMENTS TO OBTAIN A SINGLE CRITICAL MICELLE CONCENTRATION
par: Andrade-Acuña,Daniela, et autres
Publié: (2020)

Preparation, characterization, and evaluation of amphotericin B-loaded MPEG-PCL-g-PEI micelles for local treatment of oral Candida albicans
par: Zhou L, et autres
Publié: (2017)

Data on the relationship between lamotrigine and levetiracetam serum/plasma levels and toxicity: Experience at an academic medical center
par: Kelly E. Wood, et autres
Publié: (2021)

Efficacy of an Intranasal Tear Neurostimulator in Sjögren Syndrome Patients
par: Lilley J, et autres
Publié: (2021)

Cellular Responses in the Respiratory Tract Following Intranasal administration of Peste des petits Ruminant Vaccine in Goats
par: Ezeasor,C. V, et autres
Publié: (2013)

Encapsulated Escitalopram and Paroxetine Intranasal Co-Administration: In Vitro/In Vivo Evaluation
par: Soraia Silva, et autres
Publié: (2021)

Bufalin-loaded vitamin E succinate-grafted-chitosan oligosaccharide/RGD conjugated TPGS mixed micelles demonstrated improved antitumor activity against drug-resistant colon cancer
par: Yuan Z, et autres
Publié: (2018)

Development and mechanistic study of a microemulsion containing vitamin E TPGS for the enhancement of oral absorption of celecoxib
par: Subongkot T
Publié: (2019)

Characterization and Cytotoxicity of Polyprenol Lipid and Vitamin E-TPGS Hybrid Nanoparticles for Betulinic Acid and Low-Substituted Hydroxyl Fullerenol in MHCC97H and L02 Cells
par: Tao R, et autres
Publié: (2020)

FREQUENCY OF LARYNGOSPASM IN AWAKE VERSUS DEEP EXTUBATION AFTER INTRANASAL SURGERY
par: Syed Ehtesham Haider Naqvi, et autres
Publié: (2018)